Caffeine in Your Blood Could Affect Body Fat And Diabetes Risk, Study Finds
HEALTH
19 March 2023
By DAVID NIELD(Clay Banks/Unsplash)
The levels of caffeine in your blood could affect the amount of body fat you carry, a factor that in turn could determine your risk of developing type 2 diabetes and cardiovascular diseases.Those are the findings of a new study that used genetic markers to establish a more definitive link between caffeine levels, BMI, and type 2 diabetes risk.
The research team, from the Karolinska Institute in Sweden, the University of Bristol in the UK, and Imperial College London in the UK, says calorie-free caffeinated drinks could be explored as a potential means of helping reduce body fat levels.
“Genetically predicted higher plasma caffeine concentrations were associated with lower BMI and whole body fat mass,” write the researchers in their published paper.
“Furthermore, genetically predicted higher plasma caffeine concentrations were associated with a lower risk of type 2 diabetes. Approximately half of the effect of caffeine on type 2 diabetes liability was estimated to be mediated through BMI reduction.”
The study involved data from just under 10,000 people collected from existing genetic databases, focusing on variations in or near specific genes known to be associated with the speed at which caffeine is broken down. In general, those with variations affecting the genes â namely CYP1A2 and a gene that regulates it, called AHR â tend to break caffeine down more slowly, allowing it to remain in the blood longer. Yet they also tend to drink less caffeine in general.
An approach called Mendelian randomization was used to determine likely causal relationships between the presence of the variations, illnesses like diabetes, body mass, and lifestyle factors.
While there was a significant link between caffeine levels, BMI, and type 2 diabetes risk, no relationship emerged between the amount of caffeine in the blood and cardiovascular diseases including atrial fibrillation, heart failure, and stroke.
Previous studies have linked a moderate and relative increase in caffeine consumption to better heart health and a lower BMI, and the new research adds more detail to what we already know about the effects that coffee has on the body.
It’s important to also keep in mind the effects of caffeine on the body aren’t all positive, which means care must be taken when weighing up the benefits of drinking it â but this latest study is an important step in assessing how much caffeine is ideal.
“Small, short term trials have shown that caffeine intake results in weight and fat mass reduction, but the long term effects of caffeine intake is unknown,” write the researchers.
The team thinks the association shown here could be down to the way caffeine increases thermogenesis (heat production) and fat oxidation (turning fat into energy) in the body, which both play an important role in overall metabolism.
However, more research will be needed to confirm cause and effect. While this study involved a large sample, Mendelian randomization isn’t infallible, and it’s still possible that other factors are at play that weren’t accounted for in this study.
“Considering the extensive intake of caffeine worldwide, even its small metabolic effects could have important health implications,” write the researchers.
The research has been published in BMJ Medicine.
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Mars rovers tasked with hunting for traces of biology could roll over microscopic life forms without smelling a thing, simply because their instruments aren’t up to the task.
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The Sandals For Standing All Day Without Discomfort.
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Sinus Congestion Treatments Most People Might Not Know Of
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Scientists Reveal The Most Detailed Geological Model of Earth’s Past 100 Million Years
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Tyler is actually full of attractive mature women
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A New Battery In Development Means We Might Be Able to Spend The Day On Venus
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Astronomers Traced The Origins of Water to a Time Before The Sun
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Tyler: Laser Belly Fat Removal Cost (Current Price)
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Costco is Hiring Remote Jobs (See Salaries)
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Kitchen Remodeling Trends in 2023 Might Surprise You
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Bows Were Being Used in Europe 40,000 Years Earlier Than We Thought
A cave in southern France has revealed evidence of the first use of bows and arrows in Europe by modern humans some 54,000 years ago, far earlier than previously known.
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Treatments for Atrial Fibrillation (You May Be Surprised)
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The New Volvo Recharge Is A Jaw Dropper
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The Warm Women’s Boots Are Taking Texas By Storm
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Where We Get Wind From May Blow You Away
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Save Yourself From Toenail Fungus Apocalypse
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Engineers Create an ‘Impossible’ Light Sensor With an Efficiency of 200%
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The Predatory Slime Mold From The Last of Us Isn’t Actually a Fungus – It’s Weirder
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All Adults On Medicare Receive A Huge Benefit (Check If You Qualify)
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Belly Fat Removal Prices In Tyler Are Just Unbelievable (See Here).
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3 Prostate Conditions That Can Cause ED
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Trillionth-of-a-Second Shutter Speed Camera Catches Chaos in Action
To take a picture, the best digital cameras on the market open their shutter for around around one four thousandths of a second.
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First Signs of Metastatic Breast Cancer (Write These Down)
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These 2 Vegetables Will Kill Your Belly And Arm Fat Overnight!
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All Living Cells Could Have The Molecular Machinery For a ‘Sixth Sense’
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Ways To Get Rid of Mold That May Surprise You
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Millions of Dead Fish Blanket Australian River in Hypoxia Disaster
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Radioactive Leak at Minnesota Nuclear Plant Revealed Months After Accident
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First Red Flags Of Multiple Myeloma Many May Miss (Write These Down).
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Belly Fat Removal Without Surgery in Tyler: The Cost Might Surprise You
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Warning Signs of HIV Must Not Be Ignored
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Russia’s Rescue Mission to The ISS Is Expected to Launch This Week
Russia’s space agency said Saturday it was planning to send a rescue ship on February 24 to bring home three astronauts whose return vehicle was damaged by a tiny meteoroid.
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Here’s The Average Price Of Gutter Protection For Houses In US
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Experts Pick: The Best Balance Transfer Credit Card of 2023
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Some People May Not Want To Miss Red Flag Signs Of Schizophrenia
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Somehow, a Star Is Being Born in The Extremes Around Our Galaxy’s Black Hole
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You May Never Clean Your Vents The Same Way Again (Write This Down)
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This Mysterious Planet Could Be Transforming Into a Water World
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The Broken Stones of Monkeys Look Uncannily Like Something We Used to Make
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The Many Reasons For Owning An Emergency Generator Might Surprise You
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What Are The Safest Bottled Water Brands In 2023? (See The List).
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Over 65? Get Your FREE Rapid COVID Antigen Test Kits In Bulk Today!
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A Bunch of New Funnel Web Spiders Have Been Found Going Blind in Israeli Caves
Seven new funnel web spider species have been found emerging in caves in Israel, and they’re all in various stages of losing their vision.
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Revolutionary anti-snoring device sold over 1.5 million times.
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This Is How Much A Cremation Should Cost In 2023
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Cadillac Has Done It Again. This Year’s Lineup Has Left Us Speechless
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Antarctic Sea Ice Is The Lowest It’s Been in 45 Years of Records, Researchers Report
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Remove Tummy Fat Without Surgery in Tyler: The Price Might Surprise You
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1,000 Years Ago, Ancient Puebloans Built a Mysteriously Vast City. We May Finally Know How
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Blueprint of a Quantum Wormhole Teleporter Could Point to Deeper Physics
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Food for the Soul 